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L-5-Methyltetrahydrofolate Calcium

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Address: Rm 218, Tangxing Digital Bld, #6 Tangxing Rd, Xi’an, Shaanxi, China
Phone: +86 17791258855
Landline: +86 (0)29 81870046

L-5-Methyltetrahydrofolate Calcium

Other Name


Product Specification/ Purity





White to pale yellow powder


Customized various dosage forms and packaging


HACCP, ISO22000, IS09001, Eu-Organic, Us Organic, HALAL, KOSHER

L-5-Methyltetrahydrofolate Calcium

Product Description

Calcium L-5-methyltetrahydrofolate(L-5-MTHF-Ca)is a synthetic derivative of folic acid, thepredominant, naturally occurring form of folate.It’s synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt.
Levomefolate Calcium (5-MTHF), a naturally occurring salt-methyl derivative of folate, is the most biologically active and functional form of folate and is more readily absorbed than folate.


Product Specifications

Our L-5-Methyltetrahydrofolate Calcium is of 99% purity.


Certificate of Analysis


L-5-methyltetrahydrofolate (along with vitamin B12) functions as a methyl donor in a range of metabolic and neurological processes, making it critical to many metabolic pathways in the body. L-5-methyltetrahydrofolate plays a vital role in methylation. It converts homocysteine into methionine, produces 5-hydroxytryptamine and melatonin, and indirectly participates in DNA synthesis.
L-5-methyltetrahydrofolate is the strongest form of dietary folate. It is the only naturally occurring form in our blood circulation and is therefore the form of folate that is normally transported to peripheral tissues for cellular metabolism. Many people don’t know that folic acid is a synthetic form of the vitamin, which means it’s only found in fortified foods and supplements. It is the most severely oxidized form of folic acid and does not have the coenzyme activity required by the body. Therefore, it must be reduced and methylated to be metabolically active in the body. Within the cell, folate is reduced to the metabolically active “tetrahydrofolate” form.

Application Cases

Why RainWoodBiotech?

RainWood Biotech is engaged in researching, producing, and exporting concerning the field of health and fitness, cosmetics, pharmaceuticals, food, and beverages additives, and also feeding staff who have obtained EU and US organic certification, KOSHER, HALAL, ISO9001, HACCP, and ISO22000.
RainWood Biotech was established in 2006, located in Shaanxi Xi’an Hi-tech Development Zone, covering 19 acres of land with a factory construction area of around 10000 square meters.

RainWood Biotech believes that natural specialty ingredients and innovative technology are the best basis for us to serve our clients’ needs. We are capable and proud to provide the greatest product solutions to increase more value of the products themselves.

Frequently Asked Questions

Rainwood provides herbal extract, cosmetic ingredient and food additive product.

Our company has its own competitive R&D team, and currently owns more than 100 employees. Among them, there are 3 Dr. doctors majored in this field. Besides, Postgraduate employee accounts 10%, undergraduate employee accounts 15%, and professional technical personnel accounts 5%. Its professional talented personnel are completely equipped in laboratory for the quality control.
Various Detection Devices are well equipped, such as HPLC, GC, UV, TLC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
The entire production process from the source of raw material, production, inspection, warehousing, customer service and other sectors are in strict accordance with the ISO9001:2015 system.
We will provide you with satisfactory products according to your requirements.

Please contact our sales person and they will guide you with an easy and professional way for your order.

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