Search
Close this search box.

News

Product Categories

Have questions about our products?

Simply fill out the form below and one of our customer service representatives will contact you shortly.

Certificates

Contact Us

Address: Rm 218, Tangxing Digital Bld, #6 Tangxing Rd, Xi’an, Shaanxi, China
Phone: +86 17791258855
Landline: +86 (0)29 81870046
Email: info@rainwoodbio.com

This article is enough to take you through NMN

1.What is NMN?

NMN stands for nicotinamide mononucleotide, a molecule that occurs naturally in all life forms.At the molecular level, this molecule is a nucleotide, a basic structural unit of nucleic acid RNA.Structurally, it consists of nicotinamide, ribose, and phosphate groups (Figure 1).NMN is the direct precursor of the required molecule.Nicotinamide adenine dinucleotide (NAD+) is considered to be the key molecule to increase the level of NAD+ in cells.

2.What is nicotinamide adenine dinucleotide (NAD+)?

NAD+ is a coenzyme necessary for life and cell function.Enzymes are the catalysts that make biochemical reactions possible.Coenzymes are the \”helper\” molecules that enzymes need to perform their functions.

3.What does NAD+ do?

NAD+ is the most abundant molecule in the body after water, without which an organism would die.NAD+ is used in the body by many proteins, such as Sirtuins, which repair damaged DNA.It is also important for the mitochondria, the power cells that produce the chemical energy our bodies use.

4.NAD+ plays a coenzyme role in mitochondria

NAD+ plays a particularly active role in metabolic processes such as glycolysis, the TCA cycle (AKA Krebs cycle or citric acid cycle) and the electron transport chain.

As a ligand, NAD+ binds to the enzyme, transferring electrons between molecules.Electrons are the atomic basis of cell energy, and by transferring electrons from one molecule to another, NAD+ works through cellular mechanisms similar to battery charging.When electrons are used up to provide energy, the battery runs out.Without the boost, these electrons can\’t get back to where they started.In cells, NAD+ acts as a stimulant.In this way, NAD+ can reduce or increase enzyme activity, gene expression, and cell signaling.

5.NAD+ helps control DNA damage

As organisms age, they cause DNA damage due to environmental factors such as radiation, contamination and inaccurate DNA replication.According to the current aging theory, the accumulation of DNA damage is the main cause of aging.Almost all cells contain \”molecular mechanisms\” to repair this damage.This machine consumes NAD plus and energy molecules.As a result, excessive DNA damage can deplete valuable cellular resources.

An important DNA repair protein, PARP(Polyadp-Ribose polymerase), relies on NAD+ for function.NAD+ levels drop in the elderly.Accumulation of DNA damage during normal aging leads to an increase in PARP and a decrease in NAD+ concentration.Any further DNA damage in the mitochondria would exacerbate this depletion.

PARP 1 is a mediator in DNA repair

PARP1 attracts DNA machinery to repair DNA

How does PARP 1 help repair the schematic of damaged DNA

NMN is used to make NAD+, PAP1 uses NAD+

6.How does NAD+ affect sirtuins(longevity genes) activity?

NMN is used to make NAD+, sirtuins use NAD+

Newly discovered Sirtuins, also known as \”guardians of genes\”, play a crucial role in maintaining the health of cells.Sirtuins are enzymes involved in cellular stress response and damage repair.They are also involved in insulin secretion, the aging process and health conditions related to aging, such as neurodegenerative diseases and diabetes.The activation of the Sirtuins requires NAD+.

Please click here to learn more about this product infomation

NMN is one of our hot sell product. Are you worried that you can’t find good NMN? From today onwards, you don’t have to worry about that anymore.

Shaanxi Ronchn Biotech is dedicated to cosmetic industryIn this field not only have rich experience, also have a good reputation. Its aim is to create a health care raw material brand that everyone can rest assured, to solve your choice of trouble!

Similar Posts

Shilajit Extract: What It Is, How It’s Extracted, Benefits, Precautions, and More

Looking for a reliable wholesale bulk Shilajit powder manufacturer in China? Look no further! We provide high-quality Shilajit Extract powder sourced from the pristine mountains of the Himalayas. Our state-of-the-art extraction process ensures the preservation of its natural goodness. With its potential health benefits, including increased energy levels and overall vitality, our Shilajit powder is a perfect addition to your product lineup. Trust us as your trusted partner for premium Shilajit powder, offering competitive prices, exceptional quality, and efficient bulk order processing. Elevate your business with our top-notch Shilajit powder. Contact us today for wholesale inquiries!

Read More »

The Benefits of Capsaicin

Exploring Capsaicin’s Benefits Capsaicin, known for its anti-inflammatory properties, offers various health benefits across different bodily systems. Let’s delve into how capsaicin impacts overall well-being. Capsaicin’s Heart Health Benefits Research indicates that capsaicin supplementation can effectively

Read More »

Deciphering Capsaicin’s Mechanism of Action

Capsaicin: How It Works Capsaicin, derived from chili peppers, operates primarily by diminishing Substance P, a pain mediator in nerve fibers. Results from randomized controlled trials (RCTs) investigating its efficacy in treating osteoarthritis indicate its effectiveness

Read More »

Nutritional Benefits of Freeze-Dried Strawberries

Freeze-Dried Strawberries: A Nutrient-Packed Snack Freeze-dried strawberries pack a punch when it comes to nutrition, offering a concentrated source of vitamins and minerals that contribute to overall health. While the freeze-drying process may lead to some

Read More »

Nutritional Benefits of Freeze-Dried Apples

Are Freeze-Dried Apples Healthy? When it comes to healthy snacking, freeze-dried apples emerge as a popular choice. Amidst the plethora of fruit options available, freeze-dried apples offer a convenient and nutritious alternative, brimming with benefits for

Read More »

Ask For A Quick Quote

We will contact you within 1 working day, please pay attention to the email with the suffix “@rainwoodbio.com”. 

Please tell us the products you need

We will offer you free samples and a certificate of analysis

We will contact you within 1 working day, please pay attention to the email with the suffix “@rainwoodbio.com”.