Common Fenugreek Seed Extract

Product Description

Fenugreek extract is the leguminous plant Trigonella foenum-graecum L. The seeds have the functions of warming kidney, dispelling cold and relieving pain, and are used for the symptoms of kidney deficiency cold, low abdominal cold pain, small intestine hernia, cold wet beriberi and so on.

Product Specifications

The effective components of fenugreek extract are: fenugreek saponin 1%-50%, fenugreek raw powder and fenugreek oil

Certificate of Analysis

Function

1. Blood pressure lowering effect 4-hydroxyisoleucine is isolated from fenugreek, which has therapeutic effect on type

2 diabetes. Fenugreek has the effects of supplemening Yang, lowering blood sugar and lowering blood lipids, which may be related to the above amino acids.

3. Trigonelline has hypoglycemic activity in normal animals and chemically induced diabetic animals; The saponins in the extract of defatted fenugreek seed have the effect of lowering blood sugar. Galactomannan contained in fenugreek extract has significant effects on lowering blood sugar, regulating blood lipids and reducing weight.

4. Prevention and treatment of fatty liver fenugreek total saponins (TFGs) can significantly reduce serum TG,TC and LDL levels in rat fatty liver model. In addition, liver index, TG,TC,MDA,FFA and HYP contents and GST activity significantly increased the activities of SOD,NO,Na+-K+ -ATPase and Ca2+-Mg2+ -ATPase in liver, significantly reduced the extent and range of lipid drop distribution in hepatocyte plasma, and significantly inhibited the expression of hepatocyte cytochromic P450ⅡE1 .

5. Anti-ulcer effect Fenugreek seed water extract and the gel part isolated from the seed have obvious anti-ulcer activity. This effect is not only due to its inhibition of gastric acid secretion, but also has a certain effect on gastric mucosal glycoprotein. The water extract of fenugreek seed can prevent oil peroxidation caused by alcohol by improving the antioxidant capacity of gastric mucosa, thus reducing mucosal damage.

6. Anti-tumor effect The papainine contained in fenugreek seeds has significant activity against lymphoid leukemia. The trigonelline contained in the seed can prolong the life of leukemia P388 mice by 31% at the level of 12.5mg·kg-1, and has obvious inhibitory effect on mouse liver cancer (HAc). Way of the water extract of fenugreek seeds by subcutaneous injection of vaccination Ehrlich ascites carcinoma (EAC) Ehrlichascitescarcinoma, before and after vaccination in mice, the results of cancer cell growth inhibition rate of more than 70%. The number of cells and macrophages in peritoneal effluents (Chemicalbook secretion) of mice was increased.

7. Protective effect on acute and chronic chemical liver injury Fenugreek extract can effectively inhibit the elevation of serum ALT and AST in mice with acute liver injury, showing a good dose-response relationship. Fenugreek water extract has a protective effect on the liver of rats with CTC induced chronic liver injury. The mechanism of its protective effect on acute and chronic chemical liver injury of mice and rats may be lipid peroxidation and increase of GSH-Px enzyme activity. 8. The methanol extract of defatted part of fenugreek seed can significantly reduce the serum cholesterol level of normal dogs. The total extract also reduced the serum total cholesterol of diabetic hyperlipidemia dogs. Trigonelline contained in fenugreek seeds can reduce the content of total cholesterol and free cholesterol in mouse plasma.