Resveratrol is a polyphenolic compound, mainly from grape (red wine), polygonum cuspidate, peanut, mulberry, and other plants. Resveratrol has an obvious effect on preventing tumors, especially hormone-dependent tumors. It is also a chemical preventive agent for reducing platelet aggregation and preventing and treating atherosclerosis and cardiovascular and cerebrovascular diseases. It can also prevent osteoporosis, acne, and Senile dementia, and has antiviral and immunomodulatory effects. It ACTS as a monomer anti-aging enzyme in the human body, thus playing a potential role in preventing various age-related diseases and prolonging life expectancy.
Current studies have found that resveratrol’s nutritional benefits include:
Antipyretic and analgesic effects
Resveratrol has a certain antipyretic and analgesic activity in many different ways. Studies in intact mice and rats have shown that resveratrol gives gastric mucosa resistance to stress-induced ulcers caused by suppressed gastric secretion without affecting blood pressure.
Anti-cancer, anti-mutation effect
Generally speaking, the occurrence of cancer can be divided into three stages. First, DNA of normal cells is damaged. Second, cell division is accelerated into the process of cancer; The third is tumor progression. Resveratrol inhibited and even reversed the occurrence of cancer in three stages :(1) inhibition of initiation. To reduce free radical formation, phase induction Ⅱ medicine generation enzyme increased, antagonism dioxin role;(2) Inhibitory enhancement effect. Inhibition of cyclooxygenase and catalase;(3) Inhibiting development. Inhibit the proliferation of cancer cells, induce the differentiation of cancer cells, and induce the apoptosis of cancer cells. Resveratrol is expected to be an inhibitor of tyrosine protein kinase PTK. Many medical studies have found that resveratrol has an obvious inhibitory effect on breast cancer, stomach cancer, colon cancer, prostate cancer, leukemia, ovarian cancer, skin cancer, and other malignant tumor cells.
Published in the journal Science, the anticancer activity of Resveratrol, a natural product of grapes, suggests that resveratrol effectively inhibits cell activity associated with various cancer processes. As an antioxidant, mutagenic, and anti-inflammatory agent, resveratrol has been shown to have chemoprophylaxis against cancer, preventing cellular cancerism and the spread of malignant tumours, as well as inhibiting the protein chromatin kinase, which ACTS as an anti-mutation agent by blocking the function of kinases, and inhibiting cellular inflammation.
Cardioprotective effect
In the folk, it has been used to treat and prevent hyperlipidemia and arteriosclerosis with the traditional Chinese medicine Polyanthus, which is rich in resveratrol. Studies have shown that resveratrol mainly plays an anti-atherosclerosis role in the following aspects, preventing and treating coronary heart disease and thus playing a protective role in cardiovascular diseases:
1. Inhibit platelet aggregation, promote fibrinolysis and antithrombotic effect;
2. Protect vascular endothelium and inhibit endothelial cell proliferation;
3. Protect vascular smooth machine cells and inhibit their proliferation;
4. Anti-leukocyte effect;
5. Antagonize the effect of endothelin -1;
6. The function of anti-LDL oxidation.
Prevent heart and liver damage
Resveratrol has been found in animal experiments to inhibit the deposition of triglycerides and cholesterol in the liver. It can also increase aspartate aminotransferase and alanine aminotransferase levels by inhibiting liver fat peroxidation in mice. By analyzing the two enzymes in the serum, we can get the diagnostic information of the heart and liver.
Antithrombotic function
Resveratrol inhibits the synthesis of lipoxygenase, which is found in white cells, the heart, brain, lungs and spleen. So resveratrol prevents blood clots from forming in the blood vessels. It also inhibits platelet aggregation after treatment with the antihypertensive drug Clonine.
Boost immune system activity
Resveratrol also promotes burn healing by boosting the immune system. The efficacy of resveratrol in restoring inhibited cellular, humoral, and nonspecific immune functions in scalded mice has been investigated, providing a drug-dependent immunomodulatory effect on the controlled use of resveratrol. With different degree of severe burns study in mice shows that resveratrol can restore the damaged function, such as a response to antigen signal, hyperplasia and interleukins Ⅱ synthesis and by lymphocyte antibody synthesis ability. In severely burned animals treated with controlled resveratrol, neutrophil levels and their adhesion rate returned to near normal levels, and survival was extended.
Anti-oxidation, anti-free radical action
Resveratrol is a natural antioxidant in plants, which plays an antioxidant role mainly through scavenging or inhibiting the generation of free radicals, inhibiting lipid peroxidation and regulating the activity of antioxidant-related enzymes.Most of the polyhydroxy astragalus substances have antioxidant and anti-free radical effects.
Resveratrol oxidation induced besides the influence of free radicals and pharmacological function of arachidonic acid metabolism has attracted widespread interest, because the physiological metabolism involves many physiological disease is closely related to human health, such as atherosclerosis, alzheimer’s disease, viral hepatitis, stomach ulcers, inflammation and allergic reaction, etc.
Anti-inflammatory and anti-bacterial
Resveratrol has an inhibitory effect on Staphylococcus aureus, Catarrhalis, Escherichia coli, pseudomonas aerustris, and has A strong inhibitory effect on orphan virus, herpes simplex virus and enterovirus, coxsackie A, Group B.Resveratrol is anti-inflammatory by reducing the adhesion of platelets and changing the activity of platelets during the anti-inflammatory process.
Prolong life
A team of scientists in Pisa, Italy, has found that resveratrol helps fish live longer. Thirty of the more than 100 fish were given small amounts of resveratrol a day, 60 were given moderate amounts and 20 were given large amounts. The first group had little effect. The second group lived 27 percent longer and the third group 50 percent longer. This is the first time that resveratrol has been shown to prolong life in a vertebrate.
Reduce weight and reduce fat
Because resveratrol has anti-cancer, anti-oxidation, anti-inflammatory and antibacterial effect and love to the love of people, plant sources because said the French people often drink high fat content contains resveratrol, so the Frenchman’s incidence of coronary heart disease in other western countries, what do we learn from the information in the resveratrol because effectively suppress high fat prevention role. Some countries and regions have developed resveratrol and its products as dietary supplements.
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